PDAP1 Antibody (C-term) Blocking Peptide

Background:
Human PDAP1 encodes a deduced 181-amino acid protein expressed in all tissues test with the exception of liver, most abundantly in brain. PDAP1 enhances PDGFA-stimulated cell growth in mouse fibroblasts, but inhibits the mitogenic effect of PDGFB. The binding between PDGFA and PDAP1 is a low affinity/high capacity interaction, as determined by sold-phase studies.

Other Names:
28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PAP, PDGFA-associated protein 1, PAP1, PDAP1, HASPP28

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6258a was selected from the C-term region of human PDAP1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: PDAP1

Gene ID: 11333
Primary Accession: Q13442
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.