PDCD1 polyclonal, anti-human

Background:
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Other Names:
Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1

Antigen Types:
Synthetic Peptide

Gene Name:
PDCD1 {ECO:0000303|PubMed:7851902, ECO:0000312|HGNC:HGNC:8760}
Gene ID:
5133
Primary Accession: Q15116
Other Accession: NP_005009;5133;