PDCD1 polyclonal, anti-human

Background:
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Synonyms: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human PDCD1

Gene Symbol: PDCD1

Gene ID: 5133

Swiss prot: Q15116

Calculated MW: 32kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.