PDCD10 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7439
Background:
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Name:
Apoptosis related protein 15, CCM3, Cerebral cavernous malformations 3 protein, MGC1212, MGC24477, PDC10_HUMAN, PDCD 10, PDCD10, Programmed cell death 10, Programmed cell death protein 10, TF 1 cell apoptosis related protein 15, TF-1 cell apoptosis-related protein 15, TFAR15,
Application Dilution: WB: 1:500~1:2000
Specificity: PDCD10 polyclonal antibody detects endogenous levels of PDCD10 protein.
Immunogen:
Recombinant full length Human PDCD10.
MW: ~25 kDa
Swis Prot.: Q9BUL8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Name:
Apoptosis related protein 15, CCM3, Cerebral cavernous malformations 3 protein, MGC1212, MGC24477, PDC10_HUMAN, PDCD 10, PDCD10, Programmed cell death 10, Programmed cell death protein 10, TF 1 cell apoptosis related protein 15, TF-1 cell apoptosis-related protein 15, TFAR15,
Application Dilution: WB: 1:500~1:2000
Specificity: PDCD10 polyclonal antibody detects endogenous levels of PDCD10 protein.
Immunogen:
Recombinant full length Human PDCD10.
MW: ~25 kDa
Swis Prot.: Q9BUL8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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