PDCD4 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Programmed cell death protein 4(PDCD4) is a protein that in humans is encoded by the PDCD4 gene. It is mapped to 10q25.2. This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. It also encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is though to play a role in apoptosis but the specific role has not yet been determined.

Description:
Rabbit IgG polyclonal antibody for Programmed cell death protein 4 (PDCD4) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Death up-regulated gene protein antibody, Dug antibody, H731 antibody, Ma3 antibody, MGC33046 antibody, MGC33047 antibody, Neoplastic transformation inhibitor antibody, Neoplastic transformation inhibitor protein antibody, Nuclear antigen H731 antibody, Nuclear antigen H731 like antibody, Nuclear antigen H731 like protein antibody, Nuclear antigen H731-like antibody, OTTHUMP00000020483 antibody, PDCD 4 antibody, Pdcd4 antibody, PDCD4_HUMAN antibody, Programmed cell death 4 antibody, programmed cell death 4(neoplastic transformation inhibitor) antibody, Programmed cell death protein 4 antibody, Protein 197/15a antibody, Protein MA-3 antibody, RP11 348N5.4 antibody, Tis antibody, Topoisomerase-inhibitor suppressed protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human PDCD4(351-368aa LKELEVPHFHHELVYEAI), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.