PDCD4 Polyclonal Antibody

Background:
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
Death up-regulated gene protein, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor, Neoplastic transformation inhibitor protein, Nuclear antigen H731, Nuclear antigen H731 like, Nuclear antigen H731 like protein, Nuclear antigen H731-like, PDCD 4, Pdcd4, PDCD4, Programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), Programmed cell death protein 4, Protein 197/15a, Protein MA-3, Tis, Topoisomerase-inhibitor suppressed protein

Immunogen: Recombinant Human Programmed cell death protein 4 protein

Swissprot: Q53EL6

Calculated MW: 50,51 kDa
Observed MW: 56 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 0.33 mg/mL
Dilution: WB 1:500-1:1000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.