PDCD6 antibody (clone 2B4), anti-human

Background:
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.

Other Names:
Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2

Antigen Type:
Recombinant Protein

Gene Name: PDCD6
Gene ID: 10016
NCBI Accession: NP_001254485.1;NP_001254486.1;NP_001254487.1;NP_001254488.1;NP_037364.1
Primary Accession: O75340
Other Accession: BC012384
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .