PDCD6 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Synonyms: ALG-2, ALG2, PEF1B

Cellular Location: Endoplasmic reticulum membrane Endosome Nucleus Nucleus membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human PDCD6

Gene Symbol: PDCD6

Gene ID: 10016

Swiss prot: O75340

Calculated MW: 22kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100, IP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.