PDCD6 Polyclonal Antibody

Background:
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
AIP1, ALG 2, ALG-2-interacting protein 1, ALG2, ALIX, Apoptosis linked gene 2, Apoptosis linked gene 2 protein, Apoptosis-linked gene 2 protein, FLJ42309, FLJ46208, Hp95, KIAA1375, MA 3, MA3, MGC111017, MGC119050, MGC9123, PDCD 6, Pdcd6, PDCD6, PEF 1B, PEF1B, Probable calcium binding protein ALG 2, Probable calcium binding protein ALG2, Probable calcium-binding protein ALG-2, Programmed cell death 6, Programmed cell death 6-interacting protein, Programmed cell death protein 6, PS 2, PS2

Immunogen: Recombinant protein of human PDCD6

Swissprot: O75340
Gene Accession: BC012384

Calculated MW: 22 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-11255/sc-292580