PDCD6IP antibody (clone 3C4), anti-human
€435.00
In stock
SKU
AC-AT3247a
Catalog Number: AC-AT3247a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IF, E
Request Information AC-AT3247a">Request Information
Background:
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Antigen Type:
Recombinant Protein
Gene Name: PDCD6IP (HGNC:8766)
Gene ID: 10015
NCBI Accession: NP_001155901.1;NP_037506.2
Primary Accession: Q8WUM4
Other Accession: BC020066
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Antigen Type:
Recombinant Protein
Gene Name: PDCD6IP (HGNC:8766)
Gene ID: 10015
NCBI Accession: NP_001155901.1;NP_037506.2
Primary Accession: Q8WUM4
Other Accession: BC020066
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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