PDCD6IP Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP19973c
Background:
This gene encodes a protein thought to participate inprogrammed cell death. Studies using mouse cells have shown thatoverexpression of this protein can block apoptosis. In addition,the product of this gene binds to the product of the PDCD6 gene, aprotein required for apoptosis, in a calcium-dependent manner. Thisgene product also binds to endophilins, proteins that regulatemembrane shape during endocytosis. Overexpression of this geneproduct and endophilins results in cytoplasmic vacuolization, whichmay be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Target/Specificity:
The synthetic peptide sequence is selected from aa 556-570 of HUMAN PDCD6IP
Gene Name: PDCD6IP (HGNC:8766)
Gene ID: 10015
Primary Accession: Q8WUM4
Other Accession: NP_037506.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a protein thought to participate inprogrammed cell death. Studies using mouse cells have shown thatoverexpression of this protein can block apoptosis. In addition,the product of this gene binds to the product of the PDCD6 gene, aprotein required for apoptosis, in a calcium-dependent manner. Thisgene product also binds to endophilins, proteins that regulatemembrane shape during endocytosis. Overexpression of this geneproduct and endophilins results in cytoplasmic vacuolization, whichmay be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Target/Specificity:
The synthetic peptide sequence is selected from aa 556-570 of HUMAN PDCD6IP
Gene Name: PDCD6IP (HGNC:8766)
Gene ID: 10015
Primary Accession: Q8WUM4
Other Accession: NP_037506.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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