PDE1A polyclonal, anti-human, mouse, rat

Background:
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).

Synonyms: CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A

Cellular Location: Cytosol Nucleus

Immunogen:
Recombinant protein of human PDE1A

Gene Symbol: PDE1A

Gene ID: 5136

Swiss prot: P54750

Calculated MW: 61kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.