PDE1B polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms: HEL-S-79p, PDE1B1, PDES1B

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human PDE1B

Gene Symbol: PDE1B

Gene ID: 5153

Swiss prot: Q01064

Calculated MW: 61kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.