PDE4A Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Area: Cancer, Signal transduction

Synonyms:
5''-cyclic phosphodiesterase 4A, cAMP specific phosphodiesterase, cAMP-specific 3'', cAMP-specific 3', 5'-cyclic phosphodiesterase 4A, DPDE2, dunce like phosphodiesterase E2, PDE 4A, PDE4, PDE46, PDE4A, PDE4A, PDE4A11, Phosphodiesterase 4A, phosphodiesterase 4A cAMP specific, Phosphodiesterase 4A, cAMP-specific (dunce, phosphodiesterase E2 dunce homolog, Phosphodiesterase E2 dunce homolog, Drosophila, phosphodiesterase isozyme 4, phosphodiesterase type 4A11

Immunogen: Synthetic peptide of human PDE4A

Swissprot: P27815
Gene Accession: NP_001104777

Calculated MW: 98 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-25080/sc-25082/sc-25081/sc-25084/sc-25810