PDE4B polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP11684c
Catalog Number: AC-AP11684c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18545
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18545
Applications: WB, FC
Datasheet
Request Information
Background:
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4B, DPDE4
Target/Specificity:
This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.
Antigen Region:
189-217
Antigen Type: Synthetic Peptide
Gene Name: PDE4B (HGNC:8781)
Gene ID: 5142
Primary Accession: Q07343
NCBI Accession: NP_001032416.1;NP_001032417.1;NP_001032418.1;NP_002591.2
Other Accession: NP_002591.2;NP_001032418.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4B, DPDE4
Target/Specificity:
This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.
Antigen Region:
189-217
Antigen Type: Synthetic Peptide
Gene Name: PDE4B (HGNC:8781)
Gene ID: 5142
Primary Accession: Q07343
NCBI Accession: NP_001032416.1;NP_001032417.1;NP_001032418.1;NP_002591.2
Other Accession: NP_002591.2;NP_001032418.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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