PDE4D Polyclonal Antibody

Background:
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3', 5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

Research Area: Cancer, Signal Transduction

Synonyms:
PDE4D, ACRDYS2, DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1

Immunogen: Recombinant fusion protein of human PDE4D (NP_001184152.1).

Swissprot: Q08499
Gene ID: 5144

Calculated MW: 23-24 kDa/57-91 kDa
Observed MW: 110 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:20-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.