PDE5A polyclonal, anti-human

Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Synonyms: CN5A, PDE5, CGB-PDE

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human PDE5A

Gene Symbol: PDE5A

Gene ID: 8654

Swiss prot: O76074

Calculated MW: 100kDa

Recommended dilution:
WB 1:200-1000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.