PDE5A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70741
Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alternative Name:
CN5A, PDE5, CGB-PDE
Application Dilution: WB: 1:500 - 1:2000
Specificity: PDE5A polyclonal antibody detects endogenous levels of PDE5A protein.
Immunogen:
Recombinant protein of human PDE5A.
MW: ~ 100 kDa
Swis Prot.: O76074
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alternative Name:
CN5A, PDE5, CGB-PDE
Application Dilution: WB: 1:500 - 1:2000
Specificity: PDE5A polyclonal antibody detects endogenous levels of PDE5A protein.
Immunogen:
Recombinant protein of human PDE5A.
MW: ~ 100 kDa
Swis Prot.: O76074
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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