PDE5A polyclonal, anti-human, mouse, rat

Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Synonyms: CGB-PDE, CN5A, PDE5

Cellular Location: Cytosol

Immunogen:
Recombinant protein of human PDE5A

Gene Symbol: PDE5A

Gene ID: 8654

Swiss prot: O76074

Calculated MW: 100kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.