PDE5A Polyclonal Antibody

Background:
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Research Area: Cancer, Cell biology, Cardiovascular, Metabolism, Signal transduction

Synonyms:
5''-cyclic phosphodiesterase, CGB PDE, CGB-PDE, CGBPDE, cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase, cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase, cGMP binding cGMP specific phosphodiesterase, cGMP binding/cGMP specific phosphodiesterase, cGMP specific 3'5' cyclic phosphodiesterase, cGMP specific phosphodiesterase PDE5A2, cGMP specific phosphodiesterase type 5A, cGMP-binding cGMP-specific phosphodiesterase, cGMP-specific 3'', CN5A, CN5N, PDE 5, PDE 5A, PDE5, Pde5a, PDE5A, PDE5A1, Phosphodiesterase 5A, Phosphodiesterase 5A cGMP specific, Phosphodiesterase isozyme 5

Immunogen: Synthetic peptide of human PDE5A

Swissprot: O76074
Gene Accession: NP_001074

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32884