PDE6B Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12294b
Background:
Photon absorption triggers a signaling cascade in rodphotoreceptors that activates cGMP phosphodiesterase (PDE),resulting in the rapid hydrolysis of cGMP, closure of cGMP-gatedcation channels, and hyperpolarization of the cell. PDE is aperipheral membrane heterotrimeric enzyme made up of alpha, beta,and gamma subunits. This gene encodes the beta subunit. Mutationsin this gene result in retinitis pigmentosa and autosomal dominantcongenital stationary night blindness. Multiple transcript variantsencoding different isoforms have been found for this gene.
Other Names:
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, GMP-PDE beta, PDE6B, PDEB
Gene Name: PDE6B (HGNC:8786)
Gene ID: 5158
Primary Accession: P35913
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Photon absorption triggers a signaling cascade in rodphotoreceptors that activates cGMP phosphodiesterase (PDE),resulting in the rapid hydrolysis of cGMP, closure of cGMP-gatedcation channels, and hyperpolarization of the cell. PDE is aperipheral membrane heterotrimeric enzyme made up of alpha, beta,and gamma subunits. This gene encodes the beta subunit. Mutationsin this gene result in retinitis pigmentosa and autosomal dominantcongenital stationary night blindness. Multiple transcript variantsencoding different isoforms have been found for this gene.
Other Names:
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, GMP-PDE beta, PDE6B, PDEB
Gene Name: PDE6B (HGNC:8786)
Gene ID: 5158
Primary Accession: P35913
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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