PDE6D Polyclonal Antibody

Background:
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Research Area: Cancer, Signal transduction

Synonyms:
5''-cyclic phosphodiesterase subunit delta, GMP PDE delta, GMP-PDE delta, p17 protein, PDE 6, PDE 6D, PDE D, PDE6, PDE6D, PDE6D, PDED, Phosphodiesterase 6D cGMP specific, Phosphodiesterase 6D cGMP specific rod delta, Protein p17, Retinal rod photoreceptor cGMP phosphodiesterase delta, Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta, Retinal rod rhodopsin-sensitive cGMP 3''

Immunogen: Fusion protein of human PDE6D

Swissprot: O43924
Gene Accession: BC007831

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.