PDGF-B polyclonal, anti-human, mouse, rat

Background:
Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.

Synonyms: c-sis, IBGC5, PDGF-2, PDGF2, SIS, SSV

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human PDGF-B

Gene Symbol: PDGF-B

Gene ID: 5155

Swiss prot: P01127

Calculated MW: 27kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.