PDGF beta polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. This gene is mapped to 22q13.1. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. This gene plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.

Description:
Rabbit IgG polyclonal antibody for Platelet-derived growth factor subunit B (PDGFB) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Becaplermin antibody, c sis antibody, FLJ12858 antibody, Oncogene SIS antibody, PDGF 2 antibody, PDGF B antibody, PDGF B chain antibody, PDGF subunit B antibody, PDGF-2 antibody, PDGF2 antibody, Pdgfb antibody, PDGFB_HUMAN antibody, Platelet derived growth factor 2 antibody, Platelet derived growth factor B chain antibody, Platelet derived growth factor beta antibody, Platelet derived growth factor beta polypeptide (oncogene SIS) antibody, Platelet derived growth factor beta polypeptide (simian sarcoma viral (v sis) oncogene homolog) antibody, Platelet derived growth factor beta polypeptide antibody, Platelet-derived growth factor B chain antibody, Platelet-derived growth factor beta polypeptide antibody, Platelet-derived growth factor subunit B antibody, Proto-oncogene c-Sis antibody, Simian sarcoma viral (v sis) oncogene homolog antibody, SIS antibody, SSV antibody, v sis platelet derived growth factor beta polypeptide antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PDGF beta recombinant protein (Position: S82-T190). Human PDGF beta shares 89% amino acid (aa) sequence identity with both mouse and rat PDGF beta.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.