PDGF Receptor alpha (Phospho-Tyr1018) Rabbit polyclonal antibody, anti-human, mouse

Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer| composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development| wound healing| and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers.

Research Area: Cancer, Cardiovascular, Signal transduction, Stem cells

Synonyms: PDGF Receptor α , Tyr1018, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, EC 2.7.10.1, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFR-2, CD antigen CD140a

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year