PDGFR-α (phospho-Y1018) polyclonal, anti-human
€428.00
In stock
SKU
BS74011
Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Alternative Name:
CD140A, PDGFR2, PDGFR-2, RHEPDGFRA,
Application Dilution: WB: 1:500 - 1:2000
Specificity: PDGFR-α (phospho-Y1018) polyclonal antibody detects endogenous levels of PDGFR-α protein only when phosphorylated at Tyr1018.
Immunogen:
A phospho specific peptide corresponding to residues surrounding Y1018 of human PDGFRA.
MW: ~ 123 kDa
Swis Prot.: P16234
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Alternative Name:
CD140A, PDGFR2, PDGFR-2, RHEPDGFRA,
Application Dilution: WB: 1:500 - 1:2000
Specificity: PDGFR-α (phospho-Y1018) polyclonal antibody detects endogenous levels of PDGFR-α protein only when phosphorylated at Tyr1018.
Immunogen:
A phospho specific peptide corresponding to residues surrounding Y1018 of human PDGFRA.
MW: ~ 123 kDa
Swis Prot.: P16234
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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