PDGFR Alpha mouse (clone 7A3), anti-human, mouse, rat

PDGFR Alpha mouse (clone 7A3), anti-human, mouse, rat

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In stock
SKU
BT-MCA1011
Catalog Number: BT-MCA1011
Size(s): 20μL, 50μL, 100μL
Isotype: Mouse IgG
Reactivity: human, mouse, rat
Application(s): IF, ICC, IHC-p
Datasheet
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Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Research Area: Signal transduction, Cancer, Cardiovascular

Synonyms: PDGFRA

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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