PDGFR monoclonal, anti-mouse

PDGFR monoclonal, anti-mouse

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In stock
SKU
AC-AM1952b
Catalog Number: AC-AM1952b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 275CT1
Applications: WB
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Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].

Other Names:
Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1

Target/Specificity:
This PDGFRB monoclonal antibody is generated from mouse immunized with PDGFRB recombinant protein.

Gene Name: PDGFRB
Gene ID: 5159
Primary Accession: P09619
NCBI Accession: NP_002600.1
Other Accession: NP_002600.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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