PDGFRA (phospho-Y754) polyclonal, anti-human

Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Synonyms: CD140A, PDGFR-2, PDGFR2

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
A phospho specific peptide corresponding to residues surrounding Y754 of human PDGFRA

Gene Symbol: Phospho-PDGFRA-Y754

Gene ID: 5156

Swiss prot: P16234

Calculated MW: 123kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.