PDI polyclonal, anti-human, mouse, rat

Background:
Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum in eukaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. Another major function of PDI relates to its activity as a chaperone, i.e., it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI has been found to be involved in the breaking of bonds on the HIV gp120 protein during HIV infection of CD4 positive cells, and is required for HIV infection of lymphocytes and monocytes.

Alternative Name:
PDIp, Pancreas specific protein disulfide isomerase, Pancreas-specific protein disulfide isomerase, Pancreatic protein disulfide isomerase, PDA2, PDI, PDIA2, PDIA2, PDIp, PDIR, Protein disulfide isomerase A2, Protein disulfide isomerase, Protein disulfide isomerase associated 2, Protein disulfide isomerase family A member 2, Protein disulfide isomerase pancreatic, Protein disulfide-isomerase A2, Rho GDP dissociation inhibitor gamma,

Application Dilution:
WB:1:500-1:1,000
ICC:1:200
IHC:1:200

Specificity: PDI polyclonal antibody detects endogenous levels of PDI protein.

Immunogen:
peptide

MW: 58 kDa

Swiss-Prot: Q13087

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.