PDIA6 Polyclonal Antibody

Background:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Signal Transduction

Synonyms:
PDIA6, ERP5, P5, TXNDC7

Immunogen: Recombinant fusion protein of human PDIA6 (NP_005733.1).

Swissprot: Q15084
Gene ID: 10130

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.sciencedirect.com/science/article/pii/S014765131930291X