PDK2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: PDHK2

Cellular Location: Mitochondrion matrix Cytoplasm

Immunogen:
A synthetic peptide of human PDK2

Gene Symbol: PDK2

Gene ID: 5164

Swiss prot: Q15119

Calculated MW: 46kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.