PDK2 Polyclonal Antibody

Background:
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial, PDHK2, PDK2, PDK2, Pyruvate dehydrogenase kinase isoform 2, Pyruvate dehydrogenase kinase, isozyme 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial

Immunogen: Synthetic peptide of human PDK2

Swissprot: Q15119
Gene Accession: NP_002602

Calculated MW: 46 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-14484/sc-14486