PDK2 Polyclonal Antibody

Background:
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
PDK2, PDHK2, PDKII

Immunogen: Recombinant fusion protein of human PDK2 (NP_002602.2).

Swissprot: Q15119
Gene ID: 5164

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.