PDK4 polyclonal, anti-human, mouse

Background:
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Alternative Name:
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, FLJ40832, mitochondrial, Pdk4, PDK4_HUMAN, Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial, Pyruvate dehydrogenase kinase 4, Pyruvate dehydrogenase kinase isoenzyme 4, Pyruvate dehydrogenase kinase isoform 4, Pyruvate dehydrogenase kinase isozyme 4, Pyruvate dehydrogenase kinase isozyme 4 mitochondrial,

Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200

Specificity: PDK4 polyclonal antibody detects endogenous levels of PDK4 protein.

Immunogen:
Recombinant full length Human PDK4.

MW: ~46 kDa

Swis Prot.: Q16654

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.