PDK4 Polyclonal Antibody

Background:
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, FLJ40832, mitochondrial, Pdk4, PDK4, Pyruvate dehydrogenase [lipoamide] kinase isozyme 4 mitochondrial , Pyruvate dehydrogenase kinase 4, Pyruvate dehydrogenase kinase isoenzyme 4, Pyruvate dehydrogenase kinase isoform 4, Pyruvate dehydrogenase kinase isozyme 4, Pyruvate dehydrogenase kinase isozyme 4 mitochondrial

Immunogen: Synthetic peptide of human PDK4

Swissprot: Q16654
Gene Accession: NP002603

Calculated MW: 46 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.