PDLIM7 antibody (clone 2D6), anti-human
€435.00
In stock
SKU
AC-AT3264a
Catalog Number: AC-AT3264a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, IP, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, IP, E
Request Information AC-AT3264a">Request Information
Background:
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Other Names:
PDZ and LIM domain protein 7, LIM mineralization protein, LMP, Protein enigma, PDLIM7, ENIGMA
Antigen Type:
Recombinant Protein
Gene Name: PDLIM7
Gene ID: 9260
NCBI Accession: NP_005442.2;NP_976227.1;NP_998801.1
Primary Accession: Q9NR12
Other Accession: BC001093
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Other Names:
PDZ and LIM domain protein 7, LIM mineralization protein, LMP, Protein enigma, PDLIM7, ENIGMA
Antigen Type:
Recombinant Protein
Gene Name: PDLIM7
Gene ID: 9260
NCBI Accession: NP_005442.2;NP_976227.1;NP_998801.1
Primary Accession: Q9NR12
Other Accession: BC001093
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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