PDS5B Blocking Peptide (C-Term)

Background:
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Other Names:
Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, PDS5B

Target/Specificity:
The synthetic peptide sequence is selected from aa 1217-1228 of HUMAN PDS5B

Gene Name: PDS5B

Gene ID: 23047
Primary Accession: Q9NTI5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.