PDX1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Synonyms: GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1

Cellular Location: Cytoplasm Nucleus cytosol

Immunogen:
A synthetic peptide of human PDX1

Gene Symbol: PDX1

Gene ID: 3651

Swiss prot: P52945

Calculated MW: 31kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.