PDYN polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7886
Background:
The Proenkephalin precursor proteins are secreted proteins belonging to the opioid neuropeptide precursor family. The Proenkephalin proteins are proteolytically processed to form active secreted opioid peptides, which function as ligands for the ˚-type of opioid receptor. The Proenkephalin A precursor contains Synenkephalin, Leu-enkephalin and Met-enkephalin processed active peptides, while the Proenkephalin B precursor contains β-neoendorphin, Dynorphin, Leumorphin, Leu-enkephalin and rimorphin processed active peptides. β-endorphin and Met-enkephalin are endogenous opiates, while ACTH is crucial for adrenal gland stimulation to release cortisol. MSH increases melanin production in melanocytes, which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP kinase and PI 3-kinase pathways.
Alternative Name:
ADCA, Alpha neoendorphin, Beta neoendorphin, Beta-neoendorphin-dynorphin, Big Dyn, Big dynorphin, Dyn, Dyn-A17, Dyn-B, Dynorphin A, Dynorphin A(1-13), Dynorphin A(1-17), Dynorphin A(1-8), Dynorphin B, Dynorphin B(1-13), Dynorphin B-29, Enkephalin B, Leu enkephalin, Leumorphin, Neoendorphin dynorphin enkephalin prepropeptide, PDYN, PDYN_HUMAN, PENKB, Preprodnorphin, Preproenkephalin B, Prodynorphin, Proenkephalin B, Rimorphin, SCA23,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: PDYN polyclonal antibody detects endogenous levels of PDYN protein.
Immunogen:
Recombinant full length Human PDYN.
MW: ~ 28 kDa
Swis Prot.: P01213
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Proenkephalin precursor proteins are secreted proteins belonging to the opioid neuropeptide precursor family. The Proenkephalin proteins are proteolytically processed to form active secreted opioid peptides, which function as ligands for the ˚-type of opioid receptor. The Proenkephalin A precursor contains Synenkephalin, Leu-enkephalin and Met-enkephalin processed active peptides, while the Proenkephalin B precursor contains β-neoendorphin, Dynorphin, Leumorphin, Leu-enkephalin and rimorphin processed active peptides. β-endorphin and Met-enkephalin are endogenous opiates, while ACTH is crucial for adrenal gland stimulation to release cortisol. MSH increases melanin production in melanocytes, which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP kinase and PI 3-kinase pathways.
Alternative Name:
ADCA, Alpha neoendorphin, Beta neoendorphin, Beta-neoendorphin-dynorphin, Big Dyn, Big dynorphin, Dyn, Dyn-A17, Dyn-B, Dynorphin A, Dynorphin A(1-13), Dynorphin A(1-17), Dynorphin A(1-8), Dynorphin B, Dynorphin B(1-13), Dynorphin B-29, Enkephalin B, Leu enkephalin, Leumorphin, Neoendorphin dynorphin enkephalin prepropeptide, PDYN, PDYN_HUMAN, PENKB, Preprodnorphin, Preproenkephalin B, Prodynorphin, Proenkephalin B, Rimorphin, SCA23,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: PDYN polyclonal antibody detects endogenous levels of PDYN protein.
Immunogen:
Recombinant full length Human PDYN.
MW: ~ 28 kDa
Swis Prot.: P01213
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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