PDZ-RhoGEF Polyclonal Antibody

Background:
Rho guanine nucleotide exchange factor 11(ARHGEF11) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Alternative Names:
ARHGEF11, KIAA0380, Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: ARHGEF11

Storage: -20°C/1 year

NOTE: For Research Use Only