PDZK1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: CAP70, CLAMP, NHERF-3, NHERF3, PDZD1

Cellular Location: Cell membrane Cytoplasm Membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human PDZK1

Gene Symbol: PDZK1

Gene ID: 5174

Swiss prot: Q5T2W1

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.