PEBP polyclonal, anti-rat

Protein Family: Chaperones and Folding Catalysts

Pathway and Disease: Cell Growth and Death, Signal Transduction

Description:
Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer. PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes. Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate.

Alternate Names: Phosphatidylethanolamine-binding protein 1, PEBP-1, 23 kDa morphine-binding protein, HCNPpp, P23K, HCNP, Pebp1, Pbp, Pebp

Application Notes: E: 1:500-1:1,000; WB: 1:100

Accession No.: P31044

Antigen: Native PEBP protein purified from rat.

Format: Each vial contains 0.1 ml of crude serum.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.