PEG10 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12661a
Background:
This is a paternally expressed imprinted gene that encodestranscripts containing two overlapping open reading frames (ORFs),RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknotelements, which can induce a -1 nucleotide frame-shift. ORF1encodes a shorter isoform with a CCHC-type zinc finger motifcontaining a sequence characteristic of gag proteins of mostretroviruses and some retrotransposons. The longer isoform is theresult of -1 translational frame-shifting leading to translation ofa gag/pol-like protein combining RF1 and RF2. It contains theactive-site consensus sequence of the protease domain of polproteins. Additional isoforms resulting from alternatively splicedtranscript variants, as well as from use of upstream non-AUG (CUG)start codon, have been reported for this gene. Increased expressionof this gene is associated with hepatocellular carcinomas.
Other Names:
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, PEG10, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Gene Name: PEG10 {ECO:0000303|PubMed:11318613, ECO:0000312|HGNC:HGNC:14005}
Gene ID: 23089
Primary Accession: Q86TG7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This is a paternally expressed imprinted gene that encodestranscripts containing two overlapping open reading frames (ORFs),RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknotelements, which can induce a -1 nucleotide frame-shift. ORF1encodes a shorter isoform with a CCHC-type zinc finger motifcontaining a sequence characteristic of gag proteins of mostretroviruses and some retrotransposons. The longer isoform is theresult of -1 translational frame-shifting leading to translation ofa gag/pol-like protein combining RF1 and RF2. It contains theactive-site consensus sequence of the protease domain of polproteins. Additional isoforms resulting from alternatively splicedtranscript variants, as well as from use of upstream non-AUG (CUG)start codon, have been reported for this gene. Increased expressionof this gene is associated with hepatocellular carcinomas.
Other Names:
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, PEG10, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Gene Name: PEG10 {ECO:0000303|PubMed:11318613, ECO:0000312|HGNC:HGNC:14005}
Gene ID: 23089
Primary Accession: Q86TG7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review