PEG10 (clone 1B1C4), anti-human
€539.00
In stock
SKU
252844
Protein Family: Cellular Antigens
Pathway and Disease: Cell Growth and Death
Description:
PEG10 (Paternally expressed gene 10 protein) participates apoptosis and cell differentiation pathways. PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 also plays a role in cell growth promotion and hepatoma formation. PEG10 inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, PEG10 induces the formation of cellular extension, such as filopodia in association with ALK1.
Alternate Names: PEG10, Paternally expressed gene 10 protein, Retrotransposon-derived protein PEG10, Retrotransposon-derived gag-like polyprotein, Embryonal carcinima differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Retrotransposon gag domain-containing protein 3, Ty3/Gypsy-like protein, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: Q86TG7
Antigen: Purified recombinant fragment of PEG10(aa1-120) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cell Growth and Death
Description:
PEG10 (Paternally expressed gene 10 protein) participates apoptosis and cell differentiation pathways. PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 also plays a role in cell growth promotion and hepatoma formation. PEG10 inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, PEG10 induces the formation of cellular extension, such as filopodia in association with ALK1.
Alternate Names: PEG10, Paternally expressed gene 10 protein, Retrotransposon-derived protein PEG10, Retrotransposon-derived gag-like polyprotein, Embryonal carcinima differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Retrotransposon gag domain-containing protein 3, Ty3/Gypsy-like protein, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000
Accession No.: Q86TG7
Antigen: Purified recombinant fragment of PEG10(aa1-120) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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