PEG10 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP12661A
Catalog Number: AC-AP12661A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31292
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31292
Applications: FC, WB
Datasheet
Request Information
Background:
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Other Names:
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, PEG10, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Target/Specificity:
This PEG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PEG10.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: PEG10 {ECO:0000303|PubMed:11318613, ECO:0000312|HGNC:HGNC:14005}
Gene ID: 23089
Primary Accession: Q86TG7
NCBI Accession: NP_001035242.1;NP_001171890.1;NP_001171891.1;NP_055883.2
Other Accession: NP_055883.2;NP_001035242.1;NP_001171891.1;NP_001171890.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Other Names:
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, PEG10, EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
Target/Specificity:
This PEG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PEG10.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: PEG10 {ECO:0000303|PubMed:11318613, ECO:0000312|HGNC:HGNC:14005}
Gene ID: 23089
Primary Accession: Q86TG7
NCBI Accession: NP_001035242.1;NP_001171890.1;NP_001171891.1;NP_055883.2
Other Accession: NP_055883.2;NP_001035242.1;NP_001171891.1;NP_001171890.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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