PEMT Polyclonal Antibody

Background:
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
PEAMT, PEMPT, PEMT, PEMT, PEMT2, phosphatidylethanolamine N methyltransferase, Phosphatidylethanolamine N-methyltransferase, PNMT

Immunogen: Synthetic peptide of human PEMT

Swissprot: Q9UBM1
Gene Accession: NP009100

Calculated MW: 22 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.56 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.