PER3 Polyclonal Antibody

Background:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling

Synonyms:
2810049O06Rik , Cell growth inhibiting gene 13 protein, Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3, GIG13, gPER3, Growth inhibiting protein 13, HGNC:8847, hPER3, mPer3, Per3, PER3, Period 3, Period circadian clock 3, Period circadian protein 3, Period circadian protein homolog 3, Period homolog 3 (Drosophila), Period homolog 3, Period homolog 3, Drosophila, Period3

Immunogen: Fusion protein of human PER3

Swissprot: P56645
Gene Accession: BC026102

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.