Periostin polyclonal, anti-human

Quantity: 100 µg

Background:
POSTN(Periostin), also known as PN or OSF2, is a protein that in humans is encoded by the POSTN gene. The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13. Gillan et al.(2002) found that purified recombinant PN supported adhesion of ovarian epithelial cells. Shao et al.(2004) found that periostin was overexpressed by the majority of human primary breast cancers examined. Transfected tumor cell lines overexpressing periostin showed accelerated growth and angiogenesis as xenografts in immunocompromised animals. Kuhn et al.(2007) showed that extracellular periostin induced reentry of differentiated mammalian cardiomyocytes into the cell cycle.

Description:
Rabbit IgG polyclonal antibody for Periostin (POSTN) detection. Tested with WB in Human.

Synonyms:
MGC119510 antibody, MGC119511 antibody, OSF 2 antibody, OSF-2 antibody, OSF2 antibody, Osteoblast specific factor 2(fasciclin I like) antibody, osteoblast specific factor 2(fasciclin I-like) antibody, Osteoblast specific factor 2 antibody, Osteoblast specific factor antibody, Osteoblast-specific factor 2 antibody, PDLPOSTN antibody, Periodontal ligament specific periostin antibody, Periostin antibody, Periostin isoform thy2 antibody, Periostin isoform thy4 antibody, Periostin isoform thy6 antibody, Periostin isoform thy8 antibody, Periostin osteoblast specific factor antibody, PN antibody, POSTN antibody, POSTN_HUMAN antibody, RP11 412K4.1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Periostin(811-824aa DTPVRKLQANKKVQ), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.