PFKP Polyclonal Antibody

Background:
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
1200015H23Rik, 6 phosphofructokinase type C, 6 phosphofructokinase, platelet type, 6-phosphofructokinase, 6-phosphofructokinase type C, 9330125N24Rik, FLJ40226, K6PP, K6PP, MGC105718, PFK C, PFK, fibroblast type, PFK-C, PFKF, PFKP, Phosphofructo 1 kinase isozyme C, Phosphofructo-1-kinase isozyme C, Phosphofructokinase 1, Phosphofructokinase platelet, Phosphohexokinase, platelet type

Immunogen: Recombinant protein of human PFKP

Swissprot: Q01813
Gene Accession: BC002536

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-130227